Concepedia

Publication | Open Access

Type I Interferons in the Treatment of Pancreatic Cancer

DOIFull Paper Access

79

Citations

43

References

2007

Year

Giovanni Vitale, Casper H.J. van Eijck, Peter M. van Koetsveld Ing, Joris I. Erdmann, Ernst‐Jan M. Speel, Katy van der Wansem Ing, Diana M. Mooij, Annamaria Colao, Gaetano Lombardi, Ed Croze,
Annals of Surgery

Abstract

The antitumor activity of IFN-beta is more potent than IFN-alpha in pancreatic cancer cell lines through the induction of apoptosis. Further studies should investigate in vivo whether the intensity and distribution of IFNAR-1 and IFNAR-2c may predict the response to therapy with IFN-alpha and IFN-beta in pancreatic cancer.

References

YearCitations

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