Concepedia

Regulation of lnterleukin-5 Production by lnterleukin-4, Interferon-Alpha, Transforming Growth Factor-Beta and lnterleukin-6

H Enokihara, Yuichi Nakamura, Shigeki Nagashima, S Furusawa, Hideo Shishido

International Archives of Allergy and Immunology · 2009 · 12 citations · 0 references

Concepts

Life SciencesImmunologyCellular ImmunologyImmunoregulationCytokine BiologyCytokine Receptor SignalingCytokine RegulationImmune Cell SignalingInterferon ResponsesImmune Cell Cytokine ProductionInterleukin-5 PathwayTransforming Growth Factor Beta RegulationTransforming Growth Factor-beta Signaling

Abstract

Normal lymphocytes produce IL-5 with PHA and PMA stimulation. In this system, IL-5 production was enhanced by IL-4 and was inhibited by IFN alpha, TGF beta and IL-6.