A phase I/II study of imatinib plus reinduction therapy for c-kit-positive relapsed/refractory acute myeloid leukemia: inhibition of Akt activation correlates with complete response

The Importance of Diagnostic Cytogenetics on Outcome in AML: Analysis of 1,612 Patients Entered Into the MRC AML 10 Trial

David Grimwade, Helen M. Walker, Fiona Oliver et al. · Blood · 1998 · 2.6K citations · Full text

Life Sciences, Hematology, Oncology +12

Analysis of FLT3-activating mutations in 979 patients with acute myelogenous leukemia: association with FAB subtypes and identification of subgroups with poor prognosis

Christian Thiede, Christine Steudel, Brigitte Mohr et al. · Blood · 2002 · 1.7K citations · Full text

Medicine, Genetics, Hematology +14

Inhibition of c-kit receptor tyrosine kinase activity by STI 571, a selective tyrosine kinase inhibitor

Michael C. Heinrich, Diana Griffith, Brian Druker et al. · Blood · 2000 · 1.1K citations

Life Sciences, Molecular Biology, Pharmacology +16

Anthracycline Dose Intensification in Acute Myeloid Leukemia

Hugo F. Fernández, Zhuoxin Sun, Xiaopan Yao et al. · New England Journal of Medicine · 2009 · 907 citations · Full text

Medicine, Oncology, Pharmacotherapy +13

Survival of acute myeloid leukemia cells requires PI3 kinase activation

Qing Xu, Serge-Emile Simpson, Timothy J. Scialla et al. · Blood · 2003 · 474 citations · Full text

Life Sciences, Cell Biology, Oncology +14