Iodine-Catalyzed Synthesis of 12-Aryl-8,9,10,12-tetrahydro-benzo[<i>a</i>]xanthen-11-one Derivatives via Multicomponent Reaction

Abstract

Abstract Iodine efficiently catalyzes the one-pot, three-component reaction of aryl aldehyde, 2-naphthol, and cyclic 1,3-dicarbonyl compound under solvent-free conventional heating conditions to afford the corresponding 12-aryl-8,9,10,12-tetrahydro-benzo[a]xanthen-11-one derivatives. The present approach offers several advantages such as shorter reaction times, good yields, low cost, and mild reaction conditions. Keywords: Aldehydeiodinemulticomponent reaction β-naphtholsolvent-free conditionsxanthene ACKNOWLEDGMENTS We are grateful for financial support from Hebei Normal University (L2008Y05) and the Nature Science Foundation of Hebei Province (B2008000149). Notes a Isolated yield.