Palladium‐Catalyzed CN Cross‐Coupling of <i>N′</i>‐Monosubstituted Sulfondiimines with Aryl Bromides

Abstract

Abstract A general method for the N‐arylation of sulfondiimines with aryl bromides using tris(dibenzylideneacetone)dipalladium(0) [Pd 2 (dba) 3 ] and 2‐dicyclohexylphosphino‐2′,6′‐diisopropoxybiphenyl (RuPhos) as catalyst system was developed. A new benzothiazine was obtained, and a protocol for the cleavage of para ‐methoxyphenyl (PMP) groups in PMP‐protected sulfondiimines has been found, which provides access to synthetically useful NH‐derivatives, that are difficult to prepare by other means.