PubMed · 2008 · 23 citations · 3 references
Life SciencesPharmacologyPlant BiologyHepatotoxicologyPlant BiochemistryPlant PhysiologyHepatic ImpairmentHepatic MetabolismHepatic PathophysiologyHepatotoxicity MechanismsLiver DiseaseHepatoprotective AgentsHepatotoxic MechanismsHepatotoxic Plant CompoundsHerbal Medicine HepatotoxicityHerbal-induced Liver InjuryHistopathological LesionsHistopathological ToxicityLiver Injury Mechanisms
Two partially purified organic fractions designated by PR1 and PR2 of the fat free ethanol (95%) extract of aerial parts of Phyllanthus reticulatus were tested for the hepatoprotective activity in rats against CCl(4)-induced liver damage. The rats receiving the fractions showed promising hepatoprotective activity as evident from significant changes of pentobarbital-induced sleeping time, changes in serum levels of sGPT, sGOT, sALP and bilirubin and also from histopathological changes as compared to CCl(4)-intoxicated rats.
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Screening of Indian plants for biological activity: I.
Dhar Ml, Dhar Mm, Dhawan Bn et al. · PubMed · 1968 · 842 citations