Importance of thiols in the reductive binding of 2-nitroimidazoles to macromolecules

Tissue sulfhydryl groups

George L. Ellman · Archives of Biochemistry and Biophysics · 1959 · 26.2K citations

Critical Review of rate constants for reactions of hydrated electrons, hydrogen atoms and hydroxyl radicals (⋅OH/⋅O− in Aqueous Solution

George V. Buxton, C.L. Greenstock, W. Phillips Helman et al. · Journal of Physical and Chemical Reference Data · 1988 · 12.1K citations

Natural Sciences, Chemistry, Analytical Chemistry +15

A marker for hypoxic cells in tumours with potential clinical applicability

J. D. Chapman, Allan J. Franko, Janet Sharplin · British Journal of Cancer · 1981 · 308 citations

Medicine, Cancer Biology, Oncology +14

Mode of Action of Nitrofurazone

D. R. McCalla, A. P. Reuvers, Christel Kaiser · Journal of Bacteriology · 1970 · 197 citations · Full text

Life Sciences, Biochemistry, Microbiology +8

Hypoxia-dependent reduction of 1-(2-nitro-1-imidazolyl)-3-methoxy-2-propanol by Chinese hamster ovary cells and KHT tumor cells in vitro and in vivo.

Alummoottil J. Varghese, S. Gulyás, J. K. Mohindra · PubMed · 1976 · 196 citations

Medicine, Cancer Biology, Oncology +16