4‐Hydroxynonenal‐induced apoptosis in rat hepatic stellate cells: Mechanistic approach

Abstract

HNE-induced apoptosis of both CFSC-2G and HSC-T6 rat hepatic stellate cells is associated with changes in mRNA and protein expression of several apoptotic adaptors/regulators. The underlying mechanism for HNE-induced apoptosis may involve both transcriptional and translational regulatory steps.