Engineering Clostridia Neurotoxins with elevated catalytic activity

<i>Coot</i>: model-building tools for molecular graphics

Paul Emsley, Kevin Cowtan · Acta Crystallographica Section D Biological Crystallography · 2004 · 31.4K citations · Full text

Life Sciences, Bioinformatics, Biology +17

Tetanus and botulinum-B neurotoxins block neurotransmitter release by proteolytic cleavage of synaptobrevin

Giampietro Schiavo, Fabio Benfenati, Bernard Poulain et al. · Nature · 1992 · 1.8K citations

Life Sciences, Neurobiology, Neuroscience +16

A graphical user interface to the<i>CCP</i>4 program suite

Elizabeth Potterton, Peter Briggs, Maria Turkenburg et al. · Acta Crystallographica Section D Biological Crystallography · 2003 · 1.2K citations

Computing, Project Management, Visualization +13

Safety and efficacy of NeuroBloc (botulinum toxin type B) in type A–resistant cervical dystonia

Mitchell F. Brin, Mark Lew, Charles H. Adler et al. · Neurology · 1999 · 445 citations

Medicine, Neurology, Rehabilitation Medicine +16

Botulinum A Toxin Therapy: Neutralizing and Nonneutralizing Antibodies—Therapeutic Consequences

Hilke Göschel, Kai Wohlfarth, Jürgen Frevert et al. · Experimental Neurology · 1997 · 318 citations

Medicine, Immunology, Pharmacology +11