Effect of Certain Purines, and GO2 on Growth of Strain of Group A Hemolytic Streptococcus.

Abstract

SummaryRapid, heavy growth and hemolysin production of the C203S strain of Group A hemolytic streptococcus have been obtained on a medium of essentially known composition. In addition to factors reported by previous workers, we have found that thiamin, nicotinic acid, adenine or related purines, and an unknown factor which may possibly be biotin are necessary for growth of this strain. The relation of carbon dioxide tension to the purine requirement has been studied.