Journal of the American Geriatrics Society · 1990 · 34 citations · 27 references
MedicineGeriatric MedicinePhysiologyCircadian RhythmsDementiaGeriatricsAging PhysiologyCircadian Activity PatternsCircadian PhysiologyAge-related HypertensionAlzheimer Disease DementiaBlood PressureCircadian Blood Pressure VariationCircadian DisturbanceHeart RateHypertension In Older Adults
Circadian changes of the blood pressure and heart rate in elderly normotensive bedridden patients with severe dementia of the Alzheimer type (group D) were compared with those in elderly normotensive bedridden patients without dementia (group R), normotensive subjects with normal daily activity (group N), and hypertensive patients with normal daily activity (group H). In groups R, N, and H, the blood pressure increased in the afternoon and decreased at midnight; in group D, however, although it increased in the afternoon, it did not decrease at night. The circadian changes of the heart rate were similar in all four groups, showing maxima in the afternoon and minima at midnight. Thus, a specific alteration was found in the circadian rhythm of the blood pressure in patients with Alzheimer-type dementia.
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Clinical diagnosis of Alzheimer's disease
Guy M. McKhann, David A. Drachman, Marshall Folstein et al. · Neurology · 1984 · 28K citations · Full text
Cerebral Blood Flow in Dementia
Vladimir Hachinski, L. D. Iliff, E. Zilhka et al. · Archives of Neurology · 1975 · 3.2K citations
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CIRCADIAN VARIATION OF BLOOD-PRESSURE
M. W. Millar-Craig, CharlesN Bishop, E. B. Raftery · The Lancet · 1978 · 1.3K citations
Blood pressure and heart rate variabilities in normotensive and hypertensive human beings.
Giuseppe Mancia, Alberto Ferrari, L Gregorini et al. · Circulation Research · 1983 · 775 citations · Full text
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