Importance of the CD3 marker for evaluating changes in rhesus macaque CD4/CD8 T-cell ratios

Abstract

Better quantitation of the CD8+ T-cell population showed that the CD4/CD8 ratio was not inverted as had been reported, but is actually very similar to the values observed in human beings. Although the two species differ in the pattern of CD8 expression, the general immune system characteristics are very similar.