<i>Candida albicans</i>Peritonitis Successfully Treated with Amphotericin B

Abstract

THE mycotic flora of the gastrointestinal tract has been shown to increase when patients are treated with antimicrobials.1 , 2 Increased morbidity and mortality from fungous infections after -roadspectrum antimicrobial therapy have occurred throughout the world.2 3 4 A new antifungal agent amphotericin B has been used clinically and experimentally against a wide variety of fungi, with effective results. Amphotericin B is a conjugated haptene extracted from cultures of a South American strain of streptomycetacea. The drug is effective orally and parenterally, but low blood concentrations have attended its oral administratio n.5 6 Oral doses of 0.2 to 4.0 gm. daily have been used without . . .