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Celastrol inhibits growth and induces apoptotic cell death in melanoma cells via the activation ROS-dependent mitochondrial pathway and the suppression of PI3K/AKT signaling

MitophagyMitochondrial FunctionApoptosisAutophagyCell DeathTumor SuppressorRadiation OncologyMedicineCell BiologyCell SignalingMelanoma CellsOxidative Stress