Glucose‐dependent Insulin Modulation of Oscillatory Lipolysis in Perifused Rat Adipocytes

Abstract

We interpret these results to be due to insulin's ability to increase glucose uptake and conversion to alpha-GP, thus removing LC-CoA inhibition of triglyceride lipases. While the physiological importance of lipolytic oscillations remains to be determined, we hypothesize that such an oscillation may play an important role in the delivery of FFAs to the liver, beta cells, and other tissues.