pH-responsive amphiphilic hydrogel networks with IPN structure: A strategy for controlled drug release

Graft copolymers that exhibit temperature-induced phase transitions over a wide range of pH

Guohua Chen, Allan S. Hoffman · Nature · 1995 · 1.2K citations

Natural Sciences, Chemistry, Materials Science +16

Thermally on-off switching polymers for drug permeation and release

Teruo Okano, Y.H. Bae, Harvey Jacobs et al. · Journal of Controlled Release · 1990 · 612 citations

Pharmacy, Materials Science, Pharmaceutics +12

Thermo-responsive drug delivery from polymeric micelles constructed using block copolymers of poly(N-isopropylacrylamide) and poly(butylmethacrylate)

Joo Eun Chung, M. Yokoyama, Masayuki Yamato et al. · Journal of Controlled Release · 1999 · 593 citations

Pharmacy, Molecular Pharmaceutics, Pharmaceutics +16

Synthesis and Characterization of pH- and Temperature-Sensitive Poly(methacrylic acid)/Poly(<i>N</i>-isopropylacrylamide) Interpenetrating Polymeric Networks

Jing Zhang, Nicholas A. Peppas · Macromolecules · 1999 · 499 citations

Natural Sciences, Materials Science, Pharmaceutics +17

Synthesis, characterization and controlled drug release of thermosensitive IPN–PNIPAAm hydrogels

Xian‐Zheng Zhang, Daqing Wu, Chih‐Chang Chu · Biomaterials · 2003 · 467 citations

Pharmacy, Molecular Pharmaceutics, Pharmaceutics +14