Frequency of the <i>LRRK2 </i>G2019S Mutation in Siblings with Parkinson’s Disease

Abstract

The LRRK2 G2019S mutation is as frequent in families with possible autosomal recessive PD (2.2%) as in the sporadic cases published elsewhere (1.9%). The clinical features in the LRRK2-positive patients were those of typical PD, except for lower MMSE scores.