High GATA-4 Expression Associates with Aggressive Behavior, whereas Low Anti-Müllerian Hormone Expression Associates with Growth Potential of Ovarian Granulosa Cell Tumors

Abstract

The more aggressive GCTs retain a high GATA-4 expression, whereas the larger tumors lose the proliferation-suppressing AMH expression. The high GATA-4 expression in GCTs may serve as a marker of poor prognosis.