Neuronal Ca2+ sensor VILIP-1 leads to the upregulation of functional α4β2 nicotinic acetylcholine receptors in hippocampal neurons

Acetylcholine receptors containing the β2 subunit are involved in the reinforcing properties of nicotine

Marina R. Picciotto, Michèle Zoli, Roberto Rimondini et al. · Nature · 1998 · 1.3K citations

Molecular Pharmacology, Acetylcholine Receptors, Neurophysiology +12

Nicotine Activation of α4* Receptors: Sufficient for Reward, Tolerance, and Sensitization

Andrew R. Tapper, Sheri McKinney, Raad Nashmi et al. · Science · 2004 · 686 citations

Nicotine-induced Reward, Nicotine Activation, Molecular Pharmacology +16

Nicotine reinforcement and cognition restored by targeted expression of nicotinic receptors

Uwe Maskos, Brian E. Molles, Sebastián Pons et al. · Nature · 2005 · 558 citations

Tobacco Cessation, Tobacco Control, Cognitive Science +14

Nicotinic Cholinergic Receptor Binding Sites in the Brain: Regulation in Vivo

Rochelle D. Schwartz, Kenneth J. Kellar · Science · 1983 · 486 citations

Neurophysiology, Neuroanatomy, Synaptic Transmission +15

Nicotine-induced increase in neuronal nicotinic receptors results from a decrease in the rate of receptor turnover.

Xiaoyu Peng, Volodymyr Gerzanich, R Anand et al. · Molecular Pharmacology · 1994 · 390 citations