American Journal of Clinical Oncology · 1985 · 33 citations · 0 references
MedicineOncologyUrologyGenitourinary OncologyInfertilityReproductive MedicineFemale InfertilityMale InfertilityTesticular CancerTesticular DisordersTesticular FunctionTesticular PhysiologyAzoospermia DiagnosisFertility In Testicular DiseaseMale Sexual FunctionRetroperitoneal ApproachSexual Function PreservationTesticular Cancer ChemotherapyTesticular Function AssessmentTesticular Metastasis
The effects of therapy on the sexual ability and fertility of sixty-seven patients with nonseminomatous germ cell tumors of the testis were analyzed. Ten of 38 patients had subfertile sperm counts before therapy. Normal ejaculation was preserved in only 7/61 patients who underwent retroperitoneal lymph node dissection. In five of these patients, sperm analysis was done after chemotherapy; all had complete azoospermia. An effort to restore ejaculation with imipramine yielded only minimal response in 4/9 patients who received this drug. No major long-term effects on the libido were observed.