Optimization of selectivity by tuning column temperatures for series‐coupled columns in a dual‐oven GC system

Abstract

Abstract An improved optimization criterion has been introduced for computer assisted optimization of selectivity of two different capillary columns coupled in series and placed in two independently heated ovens. The suitability of this criterion, which incorporates the change of resolution power with the change of working conditions, has been verified by simultaneously tuning the temperatures of two columns differing in retention mechanism for separation of isomeric branched C 8 hydrocarbons.