Cross-linked hyaluronan versus collagen for injection treatment of glottal insufficiency: 2-year follow-up

Abstract

No long-term side-effects were found for either the hylan B gel or collagen groups after injection treatment. Both treatments resulted in significantly improved voice as rated by the patients and significantly improved glottal closure. Some resorption was noted for both substances, and approximately 25%, of the patients chose re-treatment 2 years after the initial treatment.