Purine base incorporation into erythrocyte nucleotides in hypoxanthine-guanine phosphoribosyltransferase deficiency

A familial disorder of uric acid metabolism and central nervous system function

Michael Lesch, William L. Nyhan · The American Journal of Medicine · 1964 · 1.5K citations

Clinical Disorders, Urological Research, Uric Acid Metabolism +9

Enzyme Defect Associated with a Sex-Linked Human Neurological Disorder and Excessive Purine Synthesis

J. Edwin Seegmiller, Frederick M. Rosenbloom, William N. Kelley · Science · 1967 · 1.2K citations

Sexual Disorders, Enzyme Defect Associated, Adrenal Gland +18

ENZYMATIC SYNTHESIS OF PURINE NUCLEOTIDES

Arthur Kornberg, Irving Lieberman, Ernest S. Simms · Journal of Biological Chemistry · 1955 · 252 citations · Full text

Biosynthesis, Biochemistry, Natural Sciences +3

Inherited Disorder of Purine Metabolism

Frederick M. Rosenbloom · JAMA · 1967 · 135 citations

Genetics, Pathology, Cerebral Palsy +21

Inhibition of Human Purine Nucleoside Phosphorylase

Thomas A. Krenitsky, G. B. Elion, Amanda M. Henderson et al. · Journal of Biological Chemistry · 1968 · 84 citations · Full text

Aldo-keto Reductase, Cellular Enzymology, Biochemistry +14