Further studies on ε-lysine acylase. The ω-<i>N</i>-acyl-diamino acid hydrolase activity of avian kidney

Abstract

ω-N-Acyl-diamino acids have been tested as substrates for ε-lysine acylase from animal sources. Chicken and pigeon kidney enzyme preparations hydrolyzed derivatives of lysine homologues as well as of lysine, the best substrates tested being ε-N-propionyl-lysine and ε-N-propionyl-ornithine. A modified procedure for purifying the enzyme from rat and hog kidney is presented. Some of its properties are different from those previously reported.