Neurology · 2005 · 148 citations · 7 references
Life SciencesImmunologyNeurologyInflammationNeuroimmunologyNeuroinfectious DiseasesCentral Nervous System ImmunityCerebrospinal Fluid ImmunologyChemokine NetworksNervous System PathologyNeuroinflammationNeuropathology Of InfectionCerebrospinal Fluid ChemokinesCerebrospinal Fluid Immune SignaturesCerebrospinal Fluid Inflammatory BiomarkersChemokine BiologyDiagnostic Marker DiscoveryInflammatory Neurologic DisordersNeuroinflammatory BiomarkersNeuroinflammatory Markers
Using protein expression profiling, the authors identified an upregulation of the chemokine B lymphocyte chemoattractant (BLC) in the CSF of patients with neuroborreliosis but not in patients with noninflammatory and various other inflammatory neurologic diseases. This upregulation was confirmed by ELISA, showing increased BLC levels in every neuroborreliosis patient while being undetectable in patients with noninflammatory neurologic diseases. These results point to BLC as a putative additional diagnostic marker for neuroborreliosis.
7
Lymphoid Tissue Homing Chemokines Are Expressed in Chronic Inflammation
Peter Hjelmström, Jenny Fjell, Tetsuhiko Nakagawa et al. · American Journal Of Pathology · 2000 · 194 citations · Full text