Proceedings of the National Academy of Sciences · 1937 · 89 citations · 0 references
MechanobiologyConvergent SeriesMuscle FunctionMolecular PhysiologyMyostatin Promotes GrowthMuscle InjurySarcopeniaSkeletal MusclePhysiologyCytoskeletonMedicineCell BiologyCellular PhysiologyNeuromusculoskeletal DisorderMyostatin Gene
The lack of myostatin promotes growth of skeletal muscle, and blockade of its activity has been proposed as a treatment for various muscle-wasting disorders. Here, we have examined two independent mouse lines that harbor mutations in the myostatin gene, ...