Concepedia

Attenuation of pulmonary vascular hypertension and cardiac hypertrophy with sitaxsentan sodium, an orally active ETAreceptor antagonist

Ronald G. Tilton, Christy L. Munsch, Sidney J. Sherwood, Shi‐Juan Chen, Y F Chen, Chengda Wu, Natalie Block, Richard A. F. Dixon, Tommy A. Brock

Pulmonary Pharmacology & Therapeutics · 2000 · 75 citations · 36 references

DOI

Concepts

References

36

Endothelin stimulates c‐fos and c‐myc expression and proliferation of vascular smooth muscle cells

Issei Komuro, Hiroki Kurihara, Takao Sugiyama et al. · FEBS Letters · 1988 · 733 citations

, , +16

Hypoxia induces endothelin gene expression and secretion in cultured human endothelium.

Stella Kourembanas, Philip A. Marsden, L. P. McQuillan et al. · Journal of Clinical Investigation · 1991 · 690 citations · Full text

, , +15

Contribution of endogenous endothelin-1 to the progression of cardiopulmonary alterations in rats with monocrotaline-induced pulmonary hypertension.

T. Miyauchi, Ryosuke Yorikane, Satoshi Sakai et al. · Circulation Research · 1993 · 337 citations · Full text

, , +13

Endothelin-receptor antagonist bosentan prevents and reverses hypoxic pulmonary hypertension in rats

S. J. Chen, Ya‐Fang Chen, Joan Durand et al. · Journal of Applied Physiology · 1995 · 297 citations

, , +15

Development of Crotalaria pulmonary hypertension: hemodynamic and structural study

Barbara Meyrick, W. Gamble, L Reid · American Journal of Physiology-Heart and Circulatory Physiology · 1980 · 246 citations

, , +12