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Expression monitoring by hybridization to high-density oligonucleotide arrays

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IL-6 is produced by osteoblasts and induces bone resorption.

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BMP2 activity, although dispensable for bone formation, is required for the initiation of fracture healing

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Medicine, Orthopaedic Surgery, Orthopedic Surgery +15

Recombinant human osteogenic protein-1 (hOP-1) induces new bone formation in vivo with a specific activity comparable with natural bovine osteogenic protein and stimulates osteoblast proliferation and differentiation in vitro.

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