The Conversion of Carboxylic Acids into Amides via NCS/Triphenylphosphine

Paul Fr⊘yen

Synthetic Communications · 1995 · 60 citations · 9 references

Concepts

Abstract

Abstract Amides can be generated in very high yields under mild conditions from the corresponding carboxylic acid and amine in the presence of equivalent amounts of triphenylphosphine and N-halosuccinimides, e.g., NCS or NBS.

References

9