One-pot synthesis of amides by aerobic oxidative coupling of alcohols or aldehydes with amines using supported gold and base as catalysts

Søren Kegnæs, Jerrik Mielby, Uffe Vie Mentzel, Thomas Jensen, Peter Fristrup, Anders Riisager

Chemical Communications · 2012 · 102 citations · 38 references

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Abstract

Synthesis of amides by aerobic oxidative coupling of alcohols or aldehydes with amines via intermediate formation of methyl esters is highly efficient and selective when using a catalytic system comprised of supported gold nanoparticles and added base in methanol.

References

38