Journal of the Chemical Society Perkin Transactions 1 · 1974 · 39 citations · 0 references
Natural SciencesChemistryMedicinal ChemistryOrganic ChemistrySynthetic Medicinal ChemistryHeterocyclic ChemistryOrganic SynthesisChemical CharacterizationStereochemical Structure - Activity RelationshipStereochemical Structure-activity Relationships
Evidence for the absolute stereochemistry of ancistrocladine [(1S,3S)-5(R)-(4,5-dimethoxy-2-methyl-1-naphthyl)-1,2,3,4-tetrahydro-8-methoxy-1,3-dimethylisoquinolin-6-ol](1) and ancistrocladinine[(3S)-5(R)-(4,5-dimethoxy-2-methyl-1-naphthyl)-3,4-dihydro-8-methoxy-1,3-dimethylisoquinolin-6-ol](2), based on a study of n.m.r., X-ray, c.d., and chemical data, is presented.