Publication | Closed Access
Cytotoxic peptide conjugates of dinuclear arene ruthenium trithiolato complexes
20
Citations
21
References
2014
Year
Medicinal ChemistryThiolato BridgesNatural SciencesDrug DiscoveryCytotoxic Peptide ConjugatesCoordination ComplexMolecular BiologyMolecular ComplexWater-soluble Peptide MoietyAnti-cancer AgentNon-peptide LigandCisplatin-resistant Mutant A2780cisrRadiation OncologyNovel TherapyBiomolecular Engineering
Novel dinuclear arene ruthenium trithiolato complexes containing a water-soluble peptide moiety in one of the three thiolato bridges were designed and evaluated against A2780 human ovarian cancer cells and against their cisplatin-resistant mutant A2780cisR.
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