Identification of the acidic compartment of Plasmodium falciparum‐infected human erythrocytes as the target of the antimalarial drug chloroquine.

Fluorescence probe measurement of the intralysosomal pH in living cells and the perturbation of pH by various agents.

S Ohkuma, Brian D. Poole · Proceedings of the National Academy of Sciences · 1978 · 2.2K citations · Full text

Life Sciences, Biochemistry, Cell Biology +17

Effect of weak bases on the intralysosomal pH in mouse peritoneal macrophages.

Brian D. Poole, S Ohkuma · The Journal of Cell Biology · 1981 · 754 citations · Full text

Life Sciences, Biochemistry, Physiology +15

Determination of DeltapH in Chloroplasts. 2. Fluorescent Amines as a Probe for the Determination of DeltapH in Chloroplasts

Shimon Schuldiner, Hagai Rottenberg, Mordhay Avron · European Journal of Biochemistry · 1972 · 648 citations · Full text

Life Sciences, Biochemistry, Chemistry +14

Lysosomes, pH and the Anti-malarial Action of Chloroquine

C. A. Homewood, D. C. Warhurst, W. Peters et al. · Nature · 1972 · 536 citations

Life Sciences, Biochemistry, Pharmacology +12

Binding of Diffusible Molecules by Macromolecules: Rapid Measurement by Rate of Dialysis

Sidney P. Colowick, Frances C. Womack · Journal of Biological Chemistry · 1969 · 516 citations · Full text

Life Sciences, Biochemistry, Chemistry +17