Determination of metronidazole and misonidazole and their metabolites in plasma and urine by high-performance liquid chromatography

Metronidazole (“Flagyl”). A radiosensitizer of hypoxic cells

J.C. Asquith, Josh Foster, R. L. Willson et al. · British Journal of Radiology · 1974 · 119 citations

Medicine, Medicinal Chemistry, Radiation Biophysics +14

The contribution of metronidazole and two metabolites to the mutagenic activity detected in urine of treated humans and mice.

Thomas H. Connor, M.E. Stoeckel, John R. Evrard et al. · PubMed · 1977 · 112 citations

Pharmacy, Toxicology, Drug Metabolism +8

THE ISOLATION AND IDENTIFICATION OF THE URINARY OXIDATIVE METABOLITES OF METRONIDAZOLE IN MAN

John E. Stambaugh, Louis G. Feo, R. W. Manthei · Journal of Pharmacology and Experimental Therapeutics · 1968 · 108 citations

Medicine, Pharmacokinetics, Pharmacology +10

Effectiveness of nitrofuran derivatives in sensitizing hypoxic mammalian cells to X rays

J. D. Chapman, A. P. Reuvers, J. Borsa · British Journal of Radiology · 1973 · 94 citations

Medicine, Pharmacology, Radiation Oncology +14

Phase 1 Study of High-Dose Metronidazole: A Specific<i>In Vivo</i>and<i>In Vitro</i>Radiosensitizer of Hypoxic Cells

Raul C. Urtasun, JD Chapman, Pierre R. Band et al. · Radiology · 1975 · 81 citations

Medicine, Oncology, Pharmacology +16