Concepedia

An efficient synthesis of new caffeine-based chalcones, pyrazolines and pyrazolo[3,4-b][1,4]diazepines as potential antimalarial, antitrypanosomal and antileishmanial agents

Braulio Insuasty, Juan Ramírez, Diana Becerra, Carlos Echeverry, Jairo Quiroga, Rodrigo Abonı́a, Sara M. Robledo, Iván Darío Vélez, Yulieth Upegui, July A. Muñoz,

European Journal of Medicinal Chemistry · 2015 · 95 citations · 34 references

DOI

Concepts

References

34

Statistical Method in Biological Assay.

M. J. R. Healy, D. J. Finney · Journal of the Royal Statistical Society Series A (General) · 1979 · 3.6K citations

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Efficient technique for screening drugs for activity against Trypanosoma cruzi using parasites expressing beta-galactosidase

Frederick S. Buckner, Christophe L. M. J. Verlinde, Anne Camille La Flamme et al. · Antimicrobial Agents and Chemotherapy · 1996 · 540 citations · Full text

, , +16

Antimalarial Alkoxylated and Hydroxylated Chalones:  Structure−Activity Relationship Analysis

Mei Liu, Prapon Wilairat, Mei‐Lin Go · Journal of Medicinal Chemistry · 2001 · 398 citations

, , +16

Antileishmanial Chalcones:  Statistical Design, Synthesis, and Three-Dimensional Quantitative Structure−Activity Relationship Analysis

Simon Feldbæk Nielsen, S. Brøgger Christensen, Gabriele Cruciani et al. · Journal of Medicinal Chemistry · 1998 · 291 citations

, , +17

Synthesis of novel pyrazolic analogues of chalcones and their 3-aryl-4-(3-aryl-4,5-dihydro-1H-pyrazol-5-yl)-1-phenyl-1H-pyrazole derivatives as potential antitumor agents

Braulio Insuasty, Alexis Tigreros, F. Orozco et al. · Bioorganic & Medicinal Chemistry · 2010 · 210 citations

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