ELECTROCHEMICAL ENANTIOMER-DIFFERENTIATING OXIDATION OF A RACEMIC ALCOHOL ON POLY(<scp>l</scp>-VALINE)-COATED ELECTRODES

Abstract

Abstract It was found that the enantiomer-differentiating oxidation of racemic 2,2-dimethyl-1-phenyl-1-propanol (1) to the corresponding ketone (2) occurred on poly(l-valine)-coated electrodes. This reaction seemed to be the first example of electrochemical enantiomer-differentiating reaction and to be available for kinetic optical resolution: 43% optically-pure S-(−)-1 was recovered as an unreacted part, when a half amount of starting 1 was converted using a lead dioxide anode coated doubly with polypyrrole and poly(l-valine).