Differential expression of VASA gene in ejaculated spermatozoa from normozoospermic men and patients with oligozoospermia

Abstract

The expression of VASA mRNA and protein was significantly decreased in the sperm of oligozoospermic men, which suggested the lower expression of the VASA gene might be associated with pathogenesis in some subtypes of male infertility and VASA could be used as a molecular marker for the diagnosis of male infertility.