Temporal Control of Urate Oxidase Activity in <i>Drosophila</i> : Evidence of an Autonomous Timer in Malpighian Tubules

Abstract

The appearance of urate oxidase activity in the Malpighian tubules of Drosophlia melanogaster is synchronized with the time of emergence of the imago from the puparium. A developmental clock within the Malpighian tubules specifies the time of appearances of urate oxidase activity.