Preliminary evidence for the intracellular localization of luteinizing hormones in mammalian oocytes

Abstract

Preliminary autoradiographic and immunofluorescent evidence is presented which suggests the localization of hLH beta, hCG and oLH within the oocytes of several mammalian species. Specificity of the response is supported by negative observations in the presence of cold hormone or antibodies to other proteins. The mechanism of action of these gonadotrophins in such a site remains to be defined.