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Regional mapping of the human gene encoding the novel pituitary polypeptide 7B2 to chromosome 15q13→q14 by in situ hybridization
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1989
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CytogeneticsGeneticsGenomic MechanismMolecular GeneticsGenomicsPituitary GlandPituitary DiseaseGerm Cell DevelopmentHuman GeneSitu HybridizationHybridization AnalysisKnockout MouseRegional LocalizationGenetic SequencesEndocrinologyGene ExpressionCell BiologyDevelopmental BiologyChromosome BiologyMedicineRegional Mapping
Genetic sequences encoding the novel pituitary polypeptide 7B2 were isolated from a human pituitary cDNA library. Hybridization analysis of a panel of human x mouse cell hybrids with a 7B2 cDNA probe indicated that the locus for the human 7B2 gene is probably located on chromosome 15. In situ hybridization analysis of metaphase chromosomes allowed the regional localization of the 7B2 gene to chromosome 15 at q13----q14.