Histopathology of Radiation Necrosis with Severe Peritumoral Edema after Gamma Knife Radiosurgery for Parasagittal Meningioma

Abstract

After radiosurgery peritumoral edema tends to occur in meningiomas with a parasagittal position. Radiation necrosis, infiltration of inflammatory cells, and radiation injury to the vasculature causing hyalinization of blood vessels are suggested as the underlying histopathology.