Recurrent Squamous Cell Carcinoma of the Anal Canal Predictors of Initial Treatment Failure and Results of Salvage Therapy

Abstract

These data indicate that multimodality therapy currently is being employed in the majority of patients with squamous cell carcinoma of the anal canal in the VA system. Tumor stage and method of treatment appear to affect the likelihood of development of recurrent disease. Salvage APR has curative potential. Results with salvage chemotherapy and RT are disappointing.