Identification of three homology classes of small, cryptic plasmids in intestinal Bacteroides species

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

Ulrich K. Laemmli · Nature · 1970 · 251.6K citations

Life Sciences, Microbiology, Molecular Biology +14

Detection of specific sequences among DNA fragments separated by gel electrophoresis

E.M. Southern · Journal of Molecular Biology · 1975 · 32.8K citations

Life Sciences, Molecular Biology, Molecular Genetics +12

Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I

Peter Rigby, Marianne Dieckmann, Carl Rhodes et al. · Journal of Molecular Biology · 1977 · 11.7K citations

Life Sciences, Molecular Biology, Molecular Genetics +14

Efficient transfer of large DNA fragments from agarose gels to diazobenzyloxymethyl-paper and rapid hybridization by using dextran sulfate.

Geoffrey M. Wahl, Michael Stern, George R. Stark · Proceedings of the National Academy of Sciences · 1979 · 3.4K citations · Full text

Life Sciences, Biotechnology, Molecular Biology +13

A multiple plasmid-containing Escherichia coli strain: Convenient source of size reference plasmid molecules

Francis L. Macrina, Dennis J. Kopecko, Kevin R. Jones et al. · Plasmid · 1978 · 800 citations

Life Sciences, Genetics, Microbiology +15