Review of Scientific Instruments · 1998 · 12 citations · 5 references
MedicineOncologyPathologyBiophotonicsDiagnostic ImagingGastrointestinal OncologyCancer DetectionEndoscopic SurgeryFluorescence ImagingGastrointestinal EndoscopyGastrointestinal ImagingMedical ImagingEndoscopic CamerasEndoscopic ImagingEndoscopic Optical ImagingEndoscopic VisionFluorescence EndoscopyGastrointestinal Neoplasms ImagingHigh-contrast ImagingOptical Contrast
We report a compact endoscopic imaging system suitable for the early detection of cancers throughout the gastrointestinal tract. The system incorporates a three-color camera to provide a conventional color image, a mercury lamp filtered between 360 and 450 nm to excite the photosensitizer, and an intensified camera to image the resulting fluorescence at 630 nm. Our results on over 30 resected specimens show a high optical contrast between the cancerous and healthy tissue.
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Endoscopic fluorescence detection of high-grade dysplasia in Barrett's esophagus
Masoud Panjehpour, B. F. Overholt, Tuan Vo‐Dinh et al. · Gastroenterology · 1996 · 247 citations · Full text
HEMATOPORPHYRIN AS A PHOTOSENSITIZER OF TUMORS*
Thomas J. Dougherty · Photochemistry and Photobiology · 1983 · 113 citations
Medicine, Oncology, Pharmacology +8