Rapid Communications in Mass Spectrometry · 2008 · 62 citations · 32 references
PharmacyPharmaceutical AnalysisToxicologyAnalytical ToxicologyForensic Pharmaceutical AnalysisForensic ToxicologyCannabis ToxicologyControlled Substance AnalysisDrugs Of AbuseToxicological Drug ScreeningAtmospheric Pressure PhotoionizationCannabinoid Analytical ToxicologyCannabinoid DetectionDesorption Atmospheric Pressure Chemical IonizationIllicit Drug Contaminant AnalysisIllicit Drug DetectionTablets
The feasibility of desorption atmospheric pressure photoionization (DAPPI) in the direct analysis of illicit drugs was demonstrated by the analysis of confiscated drug samples of various forms such as tablets, blotter paper, and plant resin and bloom. 3,4-Methylenedioxymethamphetamine (MDMA), amphetamine, phenazepam, and buprenorphine were detected from the analyzed tablets, lysergic acid diethylamide (LSD) and bromobenzodifuranylisopropylamine (bromo-Dragonfly, ABDF) from blotter paper, and Delta(9)-tetrahydrocannabinol (THC) and cannabinol from Cannabis Sativa bloom and resin. The amphetamines, phenazepam and ABDF showed protonated molecules independent of the solvent used, whereas buprenorphine, LSD and the cannabinoids showed molecular ions with toluene and protonated molecules with acetone as the solvent.
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