Pharmacokinetics and renal excretion of desmopressin after intravenous administration to healthy subjects and renally impaired patients

Abstract

Although desmopressin appears to be safe and well-tolerated by patients with impaired renal function, great caution should be exercised when titrating towards an efficient dosage regimen if patients with moderately or severely impaired renal function are to be treated with desmopressin at all.