Positron emission tomography with [¹⁸F]flutemetamol and [¹¹C]<scp>PiB</scp> for <i>in vivo</i> detection of cerebral cortical amyloid in normal pressure hydrocephalus patients

Abstract

[18F]Flutemetamol detects brain amyloid-β in vivo with moderate to high sensitivity and high specificity. This agent, therefore, represents a valuable new tool to study and verify the presence of amyloid-β pathology, both in patients with possible NPH and among the wider population.