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Paraproteinaemia in Sézary Syndrome
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1977
Year
Non-myelomatous Monoclonal HypergammaglobulinaemiaImmunodeficienciesImmunologyPathologyDermatologyHuman PathologyHematologyHelper T CellsNeuropathologyDown SyndromeSézary SyndromeLymphoid NeoplasiaAutoimmune DiseaseHistopathologyAutoimmunityImmunologic DiseaseSclerodermaGeneral PathologyAdult T-cell Leukemia-lymphomaMedicineConnective Tissue Disease
We have observed non-myelomatous monoclonal hypergammaglobulinaemia in a 61-year-old man with Sézary syndrome. Similar cases have not been reported before. Sézary cells of patients studied by other investigators were found to be helper T cells. The abundant production of T-lymphocytic stimuli may possibly explain in our case the occurrence of a paraprotein.