p53 Protein Overexpression in Low Grade Dysplasia (LGD) in Barrett's Esophagus: Immunohistochemical Marker Predictive of Progression

Abstract

p53 colocalization with LGD at index LGD diagnosis is a risk factor for progression of LGD. This can potentially be used to risk stratify BE LGD patients in terms of surveillance intervals or enrollment into secondary prevention studies.