Aryl Phosphoramides: Useful Electrophiles for Suzuki–Miyaura Coupling Catalyzed by a NiCl₂/dppp System (dppp=1,3‐Bis(diphenylphosphino)propane)

Abstract

Suzuki–Miyaura coupling: We disclose a new strategy for phenol activation in the first Suzuki–Miyaura coupling of phenol derivatives activated by forming aryl bis(2-oxo-3-oxazolidinyl)phosphines as a highly efficient and broadly applicable methodology for the diverse synthesis of biaryls and heterobiaryls (see scheme). The use of readily available, stable NiCl2/dppp as the catalyst system also provides an important advance. Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.